The molecule that runs the cell's power grid

NAD+ — nicotinamide adenine dinucleotide — is not exotic. Every living cell makes it and depends on it. It shuttles electrons in the reactions that turn food into ATP, and it is consumed directly by two enzyme families that sit at the center of modern aging research: the sirtuins, which regulate gene expression and stress response, and the PARPs, which participate in DNA repair. When either family works harder, the cell's NAD+ pool drains faster. That simple bookkeeping problem — supply versus demand of a single coenzyme — is one of the most active areas in biochemistry today.

What researchers study

The literature organizes itself around a few questions. How does the NAD+ pool change with age, metabolic stress, or DNA damage in a model system? What happens to sirtuin and PARP activity when NAD+ availability is raised or restricted? And by what routes can NAD+ or its precursors actually be delivered in a study design, given that the molecule is large, charged, and not trivially absorbed? That last question is practical rather than theoretical, and it is why delivery format gets its own research attention.

Two formats in our catalog

We supply NAD+ in the two formats labs ask for. The NAD+ strips carry 100 mg per strip in a dry film: shelf-stable, factory-measured, and easy to administer identically across a long protocol. The NAD+ nasal spray carries 500 mg per bottle in metered solution, for designs built around intranasal administration and the nose-to-brain transport questions that route raises.

The choice between them follows the same logic as the rest of our strips and sprays. If the delivery route is part of the research question, match the format the literature used. If the question is about NAD+ availability itself, the strip removes handling variables — no reconstitution, no measuring, nothing between the protocol and the material.

Handling notes

NAD+ is sensitive to heat, light, and moisture in solution, which is one reason the dry strip format exists. Labs typically store sealed strips at room conditions away from light, and refrigerate spray bottles once opened, per standard practice for aqueous peptide and coenzyme solutions. Both formats are labeled with compound and total content and are sold for laboratory research use only. The research summarized here describes cell and animal model systems; it is background for researchers, not a claim about any effect in people.

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